Nuclear Magnetic Resonance Facility

High-field NMR spectrometers (400–800 MHz) for structural analysis of proteins, complexes and metabolites using solution and solid-state techniques.

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Nuclear Magnetic Resonance Facility

800 MHz Nuclear Magnetic Resonance

(Varian 800 MHz NMR, Varian, Inc.)

An NMR spectrometer operating at 18.8T (800 MHz for protons) was funded through a $2.3 million NSF/EPSCoR grant (principal investigator, Richard Wittebort) and was installed in 2003 in the Molecular Imaging Research Center at the Brown Cancer Center. This system is used for the study of larger proteins and complexes using the TROSY technique. It is also equipped for solid-state (CP-MAS) NMR including a 32 mm HCN MAS probe.

700 MHz Nuclear Magnetic Resonance

(Varian 700 MHz NMR, Varian, Inc.)

500 MHz Nuclear Magnetic Resonance

(Varian 500 MHz NMR, Varian, Inc.)

400 MHz Nuclear Magnetic Resonance

(Varian 400 MHz NMR, Varian, Inc.)