Immunology
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Overview
Our immunology core allows for the expert analyses of immune responses to infectious diseases caused by various BSL2 or BSL3 pathogens. We also offer expertise in the development of assays for novel pathogens and multiple laboratory animal models. Areas of research include but are not limited to:
- Antibody responses
- Cell-cycle analyses
- Lymphoproliferation
- Live cell sorting
- Multi-color phenotypic analyses
- Multiplexed cytokine assays
- Blood chemistry and cellular differentials
The immunology core works closely with our other core facilities to lend expert support for downstream processing and analysis, examples of which include:
- BIO-Imaging core to design molecular markers and cellular tracers to investigate disease progression using in vivo and in vitro models.
- Animal core to carefully isolate a variety of tissues from animal models for characterization of immunological components.
- Microbiology core to process samples for IFA and cryotome sectioning with IHC and histological staining.
- HT biology core to design assays using novel cytometric techniques.
Instrumentation
Four lasers (405-nm, 488-nm, 561-nm and 635-nm) providing up to 12 colors for phenotypic analysis, intracellular cytokine staining and live-cell sorting
Multiplex up to 500 analytes per well with 96- and 384-well capabilities for multispecies cytockine/chemokine analysis
Allows for multispecies RBC, WBC and platelet counts
Provides multispecies blood chemistry analysis
Configured for processing 96-or 384-well plates
Costs
Our expert staff will work with you to determine the most cost-effective full-service assays to meet your research needs. Direct-use options for select instruments are also available. Please contact us for current pricing options and reagent availability.