Open-Access Bioinformatics & Sequencing Resources
This curated directory provides a gateway to essential, publicly available bioinformatics tools and datasets designed to support high-throughput biological research.
We have gathered high-impact resources—ranging from functional annotation databases to massive public repositories of raw NGS and single-cell data—to assist the broader research community. These open-access resources empower scientists to perform robust comparative analyses, validate experimental findings and leverage global data to accelerate discovery across the life sciences. Please note that this is a living resource; our list is continually reviewed and will be updated as new high-value tools and datasets emerge.
| Title | Information Available |
|---|---|
| Single Cell Expression Atlas | Gene and cell expression data across many studies |
| Human Cell Atlas | Reference maps of human cells |
| Single Cell Portal | Analysis tools and data exploration for single-cell data |
| GTEx | Gene expression across human tissue. |
| Cis-element Atlas | Regulatory elements and their target genes |
| Genetic Variants Allelic TF Binding Database | Allele-specific transcription factor binding |
| RBPgroup | RNA binding protein (RBP) information and tools |
| COSMIC | Catalogue of Somatic Mutations in Cancer |
| OncoKB | Precision oncology knowledge base |
| Human Immune Health Atlas UMAP Explorer | Interactive visualization of immune cell atlas data |
| PanglaoDB | A platform for the exploration of scRNA-seq data through a web-based interface. It contains data and metadata from human and mouse studies and these data was processed through a unified computational pipeline. In addition to enabling exploration of scRNA-seq experiments, the database provides a manually curated list of cell-type markers that can be incorporated into novel algorithms for inference of cell types. |
| CellMarker | GEPIA is a interactive web server for analyzing the RNA sequencing data. It contains expression data of 9,736 tumors and 8,587 normal samples. The samples originate from the TCGA and the GTEx projects |
| GEPIA | GEPIA is a interactive web server for analyzing the RNA sequencing data. It contains expression data of 9,736 tumors and 8,587 normal samples. The samples originate from the TCGA and the GTEx projects |
| CellWhisperer | CellWhisperer is a multimodal AI model combining transcriptomics with natural language to enable intuitive interaction with scRNA-seq datasets. |
| GtRNAdb | tRNA gene predictions made by tRNAscan-SE on complete or nearly complete genomes |
| tRNADB-CE | tRNA gene database curated manually by experts |
| T-psi-C | User friendly database of tRNA sequences and structures |
| Kids First data portal | Robust genetic and clinical data for pediatric cancer and congenital disorders |
| KM plot | Generating Kaplan Meier plot |
| RNAcentral | The non-coding RNA sequence database |