Health Outcomes

Cancer

  • Effect of N-acetyltransferase 2 genetic polymorphism on 4,4'-methylenebis(2-chloroaniline)-induced genotoxicity and oxidative stress
  • Effects of dose and human N-acetyltransferase 1 genetic polymorphism in benzidine metabolism and genotoxicity
  • Hexavalent chromium increases the metabolism and genotoxicity of aromatic amine carcinogens 4-aminobiphenyl and β-naphthylamine in immortalized human lung epithelial cells
  • Metabolism and genotoxicity of 4,4’-oxydianiline is dependent on N-acetyltransferase 2 genetic polymorphismMini-review: Human N-acetyltransferase genetic polymorphisms in susceptibility to aromatic amine and alkylaniline genotoxicity
  • Mini-review: Human N-acetyltransferase genetic polymorphisms in susceptibility to aromatic amine and alkylaniline genotoxicity
  • Multigroup prediction in lung cancer patients and comparative controls using signature of volatile organic compounds in breath samples
  • N -acetyltransferase 2 haplotype modifies risks for both dyslipidemia and urinary bladder cancer
  • Plasma Metabolomics Analysis of Polyvinyl Chloride Workers Identifies Altered Processes and Candidate Biomarkers for Hepatic Hemangiosarcoma and Its Development
  • Role of the human N-acetyltransferase 2 genetic polymorphism in metabolism and genotoxicity of 4, 4'-methylenedianiline
  • Stable Isotope Tracing Reveals an Altered Fate of Glucose in N-Acetyltransferase 1 Knockout Breast Cancer Cells
  • The effect of the rs1799931 G857A (G286E) polymorphism on N-acetyltransferase 2-mediated carcinogen metabolism and genotoxicity differs with heterocyclic amine exposure
  • Western diet unmasks transient low-level vinyl chloride-induced tumorigenesis; potential role of the (epi-)transcriptome

Cardiovascular

  • Acrolein but not its metabolite, 3-Hydroxypropylmercapturic acid (3HPMA), activates vascular transient receptor potential Ankyrin-1 (TRPA1): Physiological to toxicological implications
  • Aldose Reductase (AR) Mediates and Perivascular Adipose Tissue (PVAT) Modulates Endothelial Dysfunction of Short-Term High-Fat Diet Feeding in Mice
  • Associations of sympathetic activation with exposure to volatile organic compounds: A cross-sectional study
  • Benzene metabolites increase vascular permeability by activating heat shock proteins and Rho GTPases
  • Chronic Benzene Exposure Aggravates Pressure Overload-Induced Cardiac Dysfunction
  • Chronic Inhaled Benzene Exposure Exacerbates Atherosclerosis in LDL Receptor-Null Mice
  • Effects of electronic cigarette flavorants on human platelet aggregation ex vivo
  • Environmental exposure to volatile organic compounds is associated with endothelial injury
  • Environmental Pollution and Cardiovascular Disease: Part 1 of 2: Air Pollution
  • Environmental sustainability in cardiovascular practice: current challenges and future directions
  • Exposure to Vinyl Chloride and Its Influence on Western Diet-Induced Cardiac Remodeling
  • Exposure to volatile organic compounds - acrolein, 1,3-butadiene, and crotonaldehyde - is associated with vascular dysfunction
  • Exposure to Volatile Organic Compounds and Blood Pressure in NHANES 2011 to 2018
  • Exposure to Volatile Organic Compounds Is Associated with Hypertension in Black Adults: The Jackson Heart Study
  • Fine particulate matter air pollution and aortic perivascular adipose tissue: Oxidative stress, leptin, and vascular dysfunction
  • Metabolic Pathways for Removing Reactive Aldehydes are Diminished in Atrophic Muscle During Heart Failure
  • Metallomics in pulmonary arterial hypertension patients
  • Myeloid-Specific Deletion of Epsins 1 and 2 Reduces Atherosclerosis by Preventing LRP-1 Downregulation
  • Potential Roles of Metals in the Pathogenesis of Pulmonary and Systemic Hypertension
  • Reply: Urinary Metal Levels and Coronary Artery Calcification: Potential Confounders
  • Role of the Transient Receptor Potential Ankyrin-1 in the Pulmonary, Vascular, and Systemic Effects of Short-Term Acrolein Inhalation in Mice: Implications for the Toxicity of Electronic Nicotine Delivery Systems
  • Subclinical markers of cardiovascular toxicity of benzene inhalation in mice
  • TRPA1 channel contributes to myocardial ischemia-reperfusion injury
  • Urinary Metal Levels and Coronary Artery Calcification: Longitudinal Evidence in the Multi-Ethnic Study of Atherosclerosis (MESA)

Metabolic

  • Acetylator Genotype-Dependent Dyslipidemia in Rats Congenic for N-Acetyltransferase 2.
  • Altered splicing factor and alternative splicing events in a mouse model of diet- and polychlorinated biphenyl-induced liver disease
  • Associations Between Residential Exposure to Volatile Organic Compounds and Liver Injury Markers
  • Associations between residential volatile organic compound exposures and liver injury markers: The role of biological sex and race
  • Benzene Exposure Induces Insulin Resistance in Mice
  • Blood BTEXS and heavy metal levels are associated with liver injury and systemic inflammation in Gulf states residents
  • Can Zinc Supplementation Attenuate High Fat Diet-Induced Non-Alcoholic Fatty Liver Disease?
  • Changes in m6A in Steatotic Liver Disease
  • Circulating MicroRNAs, Polychlorinated Biphenyls, and Environmental Liver Disease in the Anniston Community Health Survey
  • Community-Based Evaluation of the Associations Between Well-Being and Cardiovascular Disease Risk
  • Dioxin-like and non-dioxin-like PCBs differentially regulate the hepatic proteome and modify diet-induced nonalcoholic fatty liver disease severity
  • Disruption of the mouse liver epitranscriptome by long-term aroclor 1260 exposure
  • Effect of Epidermal Growth Factor Treatment and Polychlorinated Biphenyl Exposure in a Dietary-Exposure Mouse Model of Steatohepatitis
  • Effect of vinyl chloride exposure on cardiometabolic toxicity
  • Effects of Environmental Polycyclic Aromatic Hydrocarbons Exposure and Pro-Inflammatory Activity on Type 2 Diabetes Mellitus in US Adults
  • Environmental perfluoroalkyl acid exposures are associated with liver disease characterized by apoptosis and altered serum adipocytokines
  • Environmental Pollution and the Developmental Origins of Childhood Liver Disease
  • Epidermal Growth Factor Receptor Signaling Disruption by Endocrine and Metabolic Disrupting Chemicals
  • Hepatic Injury Caused by the Environmental Toxicant Vinyl Chloride is Sex-Dependent in Mice
  • Hepatic signalling disruption by pollutant Polychlorinated biphenyls in steatohepatitis
  • Heterocyclic amines reduce insulin-induced AKT phosphorylation and induce gluconeogenic gene expression in human hepatocytes
  • Identifying sex differences arising from polychlorinated biphenyl exposures in toxicant-associated liver disease
  • Induction of glucose production by heterocyclic amines is dependent on N-acetyltransferase 2 genetic polymorphism in cryopreserved human hepatocytes
  • Insecticide and metal exposures are associated with a surrogate biomarker for non-alcoholic fatty liver disease in the National Health and Nutrition Examination Survey 2003-2004
  • Interaction of volatile organic compounds and underlying liver disease: a new paradigm for risk
  • Investigating the Acute Metabolic Effects of the N-Methyl Carbamate Insecticide, Methomyl, on Mouse Liver
  • Investigating the effects of long-term Aroclor 1260 exposure on fatty liver disease in a diet-induced obesity mouse model
  • Liver Disease in a Residential Cohort With Elevated Polychlorinated Biphenyl Exposures
  • Mechanisms of Environmental Contributions to Fatty Liver Disease
  • Metabolic effects of heterocyclic amines on insulin‑induced AKT phosphorylation and gluconeogenic gene expression are modified by N-acetyltransferase 2 genetic polymorphism
  • Obesity I: Overview and molecular and biochemical mechanisms
  • Obesity II: Establishing causal links between chemical exposures and obesity
  • Perfluorooctane sulfonate exposure and alcohol-associated liver disease severity in a mouse chronic-binge ethanol feeding model
  • Polychlorinated Biphenyl Exposure Alters tRNA Transcriptome in High-Fat Diet-Fed Mouse Liver
  • Polychlorinated biphenyl exposures differentially regulate hepatic metabolism and pancreatic function: Implications for nonalcoholic steatohepatitis and diabetes
  • Polychlorinated biphenyls alter hepatic m6A mRNA methylation in a mouse model of environmental liver disease
  • Polychlorinated Biphenyls and Nonalcoholic Fatty Liver Disease
  • Polychlorinated biphenyls, polychlorinated dibenzo-p-dioxins, polychlorinated dibenzofurans, pesticides, and diabetes in the Anniston Community Health Survey follow-up (ACHS II): single exposure and mixture analysis approaches
  • Proteomic Analysis Reveals Novel Mechanisms by Which Polychlorinated Biphenyls Compromise the Liver Promoting Diet-Induced Steatohepatitis
  • Sex differences in toxicant-associated fatty liver disease
  • Sex-specific effects of acute chlordane exposure in the context of steatotic liver disease, energy metabolism and endocrine disruption
  • The environmental pollutant, polychlorinated biphenyl 126, alters liver function in a rodent model of alcohol-associated liver disease
  • Tributyrin Inhibits Ethanol-Induced Epigenetic Repression of CPT-1A and Attenuates Hepatic Steatosis and Injury
  • Urinary acrolein metabolite levels in severe acute alcoholic hepatitis patients
  • Vinyl chloride dysregulates metabolic homeostasis and enhances diet-induced liver injury in mice
  • Vinyl chloride enhances high-fat diet-induced proteome alterations in the mouse pancreas related to metabolic dysfunction
  • Whole life exposure to low dose cadmium alters diet-induced NAFLD

Other

  • A multi-ethnic polygenic risk score for chronic kidney disease is associated with increased risk of hypertension in African American individuals
  • Depression and anxiety in a manganese-exposed community
  • Lipid peroxidation products in human health and disease 2014
  • Perceived Benefits of Nature in Diverse Populations