Spectrum News 1: New UofL study shows nicotine in e-cigarettes may not be harmless

October 23, 2026

 

LOUISVILLE, Ky. — Dr. Alex Carll is an assistant professor at the University of Louisville’s School of Medicine Physiology Department who has been studying the effects of e-cigarettes for more than six years.

“We examined the impacts of freebase nicotine, nicotine salts, and then something intended to simulate synthetic nicotine. These three different types of nicotine have sort of been involved in the evolution of e-cigarettes,” said Carll. 

Carll’s study compared heart rate data in mice exposed to vape aerosols containing the different types of nicotine. He’s found that the nicotine found in e-cigarettes may not be as harmless as some people may think.

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