Center for Cardiometabolic Science

The Center for Cardiometabolic Science houses the greatest concentration of cardiovascular researchers at the University of Louisville and in our region of the country.

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Expertise & Excellence

Cardiometabolic disease is the leading cause of morbidity and mortality. This challenge demands integrative, mechanism-driven solutions. At our Center, we unite investigators across cardiovascular biology, metabolism, immunology, genomics and physiology to address the most pressing questions for human health. Our approach is mechanistic, collaborative and translational.

Why the Center for Cardiometabolic Science?

Integrated, Systems-Level Science

We move beyond single-organ silos to study physiological function across interconnected systems.

Advanced Research Platforms

Our shared cores provide standardized, high-quality phenotyping, imaging, metabolic, and molecular capabilities.

Collaborative Culture

Faculty, staff, trainees and other partners work together in a highly interactive, team-science environment.

Translational Impact

Our work informs therapeutic development, biomarker discovery and disease modeling relevant to human health.

Program Areas

The Center influences the national direction of cardiovascular research. The main scientific themes of the Center are metabolism, inflammation and fibrosis.

Metabolism

Metabolism is foundational for life. The Center addresses how nutrition can be used as building blocks to sustain organ structure and how derangements in metabolism impair function.

Inflammation

Immune responses allow the body to respond to acute and chronic changes. The Center investigates innovative, mechanistic aspects of inflammation in health and disease.

Fibrosis

In response to injury, most organs undergo a degree of fibrosis. The heart is conspicuous in its propensity to form scar (fibrotic) tissue and lead to heart failure.